The Second London Baptist Confession of 1689, chapter 26, section 4 reads:
The Lord Jesus Christ is the Head of the church, in whom, by the appointment of the Father, all power for the calling, institution, order or government of the church, is invested in a supreme and sovereign manner; neither can the Pope of Rome in any sense be head thereof, but is that antichrist, that man of sin, and son of perdition, that exalts himself in the church against Christ, and all that is called God; whom the Lord shall destroy with the brightness of his coming.
Many interpret this section of the Confession as a dogmatic, specific identification of the office of the papacy as the Antichrist. This unfortunately leads many modern Particular Baptists who hold varying views on eschatology to reject the Confession, or at least take exception to this section or phrase. However, Sam Renihan at Particular Voices has provided a section from the writings of John Bunyan which would seem to indicate that the historic Particular Baptists used the terms antichrist, man of sin, and son of perdition in a broader sense, so that the papacy may be considered merely a representative of the spirit of antichrist, not to the exclusion of other antichrists.
Read Bunyan’s comparison of Christ and Antichrist here.